Clinical Characteristics and Pharmacological Management of COVID-19 Vaccine–Induced Immune Thrombotic Thrombocytopenia With Cerebral Venous Sinus Thrombosis: A Review

The COVID-19 pandemic saw one of the fastest developments of vaccines in an effort to combat an out-of-control pandemic. The 2 most common COVID-19 vaccine platforms currently in use, messenger RNA (mRNA) and adenovirus vector, were developed on the basis of previous research in use of this technology…

SVM Communications: Vaccine-induced immune thrombotic thrombocytopenia (VITT) – what the vascular medicine physician should know

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the rapid development of highly effective vaccines, which have proven to be the most important tool in combating the coronavirus disease 2019 (COVID-19) pandemic. Initial clinical trials reported no major adverse events beyond rare cases of anaphylaxis…

Complicanze tromboemboliche post-vaccinazione anti-COVID-19 con Vaxzevria (ChAdOx1 nCov-19, AstraZeneca) o con COVID-19 Vaccine Janssen (Ad.26. COV2.S, Johnson & Johnson)

In soggetti recentemente sottoposti a vaccinazione anti-SARS-CoV-2 con i vaccini a vettore virale Vaxzevria (ChAdOx1 nCov-19 della ditta Astra Zeneca) e con COVID-19 Vaccine Janssen (Ad.26.COV2.S della ditta Johnson & Johnson) sono state riportate diverse segnalazioni di eventi trombotici in sedi atipiche (trombosi dei seni venosi cerebrali e/o del distretto splancnico), associati a piastrinopenia e con decorsi clinici di particolare gravità…

US Case Reports of Cerebral Venous Sinus Thrombosis With Thrombocytopenia After Ad26.COV2.S Vaccination, March 2 to April 21, 2021

Cerebral venous sinus thrombosis (CVST) with thrombocytopenia, a rare and serious condition, has been described in Europe following receipt of the ChAdOx1 nCoV-19 vaccine (Oxford/AstraZeneca), which uses a chimpanzee adenoviral vector. A mechanism similar to autoimmune heparin-induced thrombocytopenia (HIT) has been proposed…

Echocardiography, lung ultrasound, and cardiac magnetic resonance findings in COVID-19: A systematic review

The manifestations of COVID-19 as outlined by imaging modalities such as echocardiography, lung ultrasound (LUS), and cardiac magnetic resonance (CMR) imaging are not fully described. We conducted a systematic review of the current literature and included studies that described cardiovascular manifestations of COVID-19 using echocardiography, CMR, and pulmonary manifestations using LUS…

Incontri di Aggiornamento in Ecografia. ECD dei Tronchi Sovraortici – 6 Maggio 2021

Carissime/i,
Il secondo Incontro di Aggiornamento, attivato con il format Live Webinar, è stato “L’ECD dei tronchi Sovraortici ” e si e’ tenuto giovedì 6 Maggio su piattaforma e-learning. L’evento rientra nel percorso formativo intitolato “Incontri di Aggiornamento in Ecografia” che, per il 2021, si terrà integralmente in digitale e prevede 3 Incontri…

Venous thromboembolism in patients with COVID-19 (SARS- CoV-2 infection) – a position paper of the German Society of Angiology (DGA)

As observed in other infections with a systemic inflammatory response, severe COVID-19 is associated with hypercoagulability and a prothrombotic state. Currently, there is growing evidence that pulmonary embolism and thrombosis contribute to adverse outcomes and increased mortality in critically ill patients with COVID-19…

The vascular side of COVID-19 disease

The SARS-CoV-2 infection (COVID-19) is causing an ongoing pandemic and potentially fatal disease. Development of coagulopathy with thrombotic complications such as deep vein thrombosis and pulmonary embolism are emerging as factors for progression to severe disease and death. Also, a markedly increased level of D-dimer, a protein product of fibrin degradation, has been associated to mortality…