COVID-19: An executive report

Accademia Nazionale dei Lincei – Commissione Salute

Maurizio Cecconi, Guido Forni, Alberto Mantovani


At a time when Italy and all world is dramatically faced with the challenge of the SARS-Cov-2 infection, hitting many aspects of human civilization, Commissione Salute of the Accademia Nazionale dei Lincei felt that it is part of its social responsibility to provide the society at large with an Executive Summary of the current status of understanding of origin, pathogenesis, and treatment of COVID-19 pandemic.

This Report is not a comprehensive review of the state-of-the-art of the field but rather snapshot of a field undergoing rapid evolution, with a daily flood of scientific publications and non-peer reviewed reports. Preparing a digest is per se a risky endeavor and the extensors of this report are well aware of their own limitations.

With the limits of the metaphor, we are experiencing wartime medicine and wartime scientific research. We are called to respond to the drama of patients at times with empiric approaches. Yet rigorous assessment remains a must and striking a balance between emergency and methodological stringency represents a major challenge.
Hopefully, with the above mentioned cautionary notes, this report will provide provisional tools to understand and cope with the unprecedented challenge we are facing.

March 25, 2020