Pulmonary embolism and screening for concomitant proximal deep vein thrombosis in noncritically ill hospitalized patients with coronavirus disease 2019

Álvaro Dubois-Silva, Cristina Barbagelata-López, Álvaro Mena, Patricia Piñeiro-Parga, Diego Llinares-García, Santiago Freire-Castro


Dear Editor,

Coagulation abnormalities with elevated D-dimer levels have been identified as predictors of poor prognosis in patients with coronavirus disease 2019 (COVID-19) in China. The correlation between D-dimer levels and diagnosis and prognosis of venous thromboembolism (VTE) has been widely described. Thus, many questions regarding the relationship between these entities are emerging.
Recently, a VTE prevalence of 25% has been reported in patients with severe novel coronavirus pneumonia. However, there is limited information about the clinical characteristics of noncritically ill hospitalized patients with COVID-19 who develop pulmonary embolism (PE), or their prevalence of lower limb concomitant deep-vein thrombosis (DVT). Therefore, the purpose of this study was to analyze the clinical data and assess the prevalence of concomitant proximal DVT in COVID-19 nonintensive care unit (non-ICU) patients with PE.

Keywords: Coronavirus disease 2019, Pulmonary embolism, Deep vein thrombosis, Screening, Coagulopathy

Internal and Emergency Medicine (2020) 15:865–870
DOI: https://doi.org/10.1007/s11739-020-02416-x
© Società Italiana di Medicina Interna (SIMI) 2020