A remarkably high incidence of VTE has been reported among critically ill patients with COVID‐19 assisted in the Intensive Care Unit (ICU). However, VTE burden among non‐ICU patients hospitalized for COVID‐19 that receive guideline‐recommended thromboprophylaxis is unknown…
Standard evaluation and management of the patient with suspected or proven cardiovascular complications of COVID-19, the disease caused by severe acute respiratory syndrome–related coronavirus-2 (SARS-CoV-2), is challenging…
Coronavirus disease 2019 (COVID-19) continues to cause considerable morbidity and mortality worldwide. Case reports of hospitalized patients suggest that COVID-19 prominently affects the cardiovascular system, but the overall impact remains unknown…
Patients with coronavirus disease 2019 (COVID-19) have elevated D-dimer levels. Early reports describe high venous thromboembolism (VTE) and disseminated intravascular coagulation (DIC) rates, but data are limited…
An ongoing global pandemic of viral pneumonia (coronavirus disease [COVID-19]), due to the virus SARS-CoV-2, has infected millions of people and remains a threat to many more. Most critically ill patients have respiratory failure and there is an international effort to understand mechanisms and predictors of disease severity. Coagulopathy, characterized by elevations in D-dimer and fibrin(ogen) degradation products (FDPs), is associated with critical illness and mortality in patients with COVID-19…
Emerging evidence shows that severe coronavirus disease 2019 (COVID-19) can be complicated by a significant coagulopathy, that likely manifests in the form of both microthrombosis and VTE. This recognition has led to the urgent need for practical guidance regarding prevention, diagnosis, and treatment of VTE…
SARS-CoV-2 pneumonia patients present with coagulation disorders and marked susceptibility to thrombosis. However, the exact prevalence of DVT has been poorly investigated while the risk seems increased in ICU patients. Therefore, we decided to perform routine duplex ultrasound examination of the lower limb veins systematically, in order to administer appropriate anticoagulation in all intubated and mechanically ventilated patients with SARS-CoV-2 pneumonia…
There is an urgent need to identify patients at high risk during the ongoing coronavirus disease (COVID- 19) pandemic. Whether a history of stroke is associated with increased severity of disease or mortality is unknown…
Coronavirus disease (COVID-19) is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is responsible for the ongoing 2019–2020 pandemic. Venous thromboembolism (VTE), a frequent cardiovascular and/or respiratory complication among hospitalized patients, is one of the known sequelae of the illness…
This case series reports a systematic assessment of deep vein thrombosis among patients in an intensive care unit in France with severe coronavirus disease 2019 (COVID-19)…
There has been a recent report of large artery ischaemic stroke among young patients with coronavirus disease 2019 (COVID-19) in the USA. The cause is felt to include coagulopathy and vascular endothelial dysfunction…
Coronavirus disease 2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may predispose patients to thrombotic disease, both in the venous and arterial circulations, due to excessive inflammation, platelet activation, endothelial dysfunction, and stasis…
In the rapidly evolving management of seriously ill patients affected with coronavirus disease 2019 (COVID-19) there is usually insufficient evidence available to make true practice guidelines. The question responses represent the opinion of a group of venous specialists who have reviewed the currently available evidence and have communicated with specialists in high volume sites in the US and internationally…
Solid data is lacking, but an emerging body of evidence suggests that COVID-19 may predispose patients to arterial and venous thrombotic disease, and that some of the therapies under investigation may pose distinct drug-drug interactions with common antithrombotic medications…
We report five cases of large-vessel stroke in patients younger than 50 years of age who presented to our health system in New York City. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was diagnosed in all five patients…
La comunità scientifica desidera contribuire al governo di questa emergenza, proponendo un modello di gestione del paziente con ictus cerebrale acuto che tenga conto della nuova realtà epidemiologica e, soprattutto, della rimodulazione del setting in cui gli operatori sanitari, e in particolare i Neurologi coinvolti nella cura del paziente con ictus, sono chiamati ad operare…
Partendo dalle evidenze presenti in letteratura, lo scopo di questo articolo è analizzare i possibili meccanismi coinvolti nel processo coagulativo a seguito dell’infezione da COVID-19 e quali potrebbero essere le strategie terapeutiche vascolari da poter attuare…
We report a case-series of COVID-19 patients with pulmonary embolism (PE) in our institution. Lille University Hospital is the tertiary care center for the North-of-France, the 2nd French region in population density (189 p/km2), also considered as a “metabolic” area with high number of overweight patients. The study was approved by the Institutional data protection authority of Lille University Hospital…
L’attuale grave epidemia, o forse pandemia, del nuovo coronavirus COVID-19 emerso in Cina a Wuhan alla fine del 2019 ha dimostrato di avere un devastante impatto planetario di salute pubblica. Le implicazioni cardiologiche del coronavirus COVID-19 sono tutt’altro che marginali e costituiscono l’occasione per richiamare l’attenzione del cardiologo sulle rilevanti interazioni tra infezioni da virus respiratori o altri agenti patogeni e rischio cardiovascolare…
The present COVID-19 outbreak emphasizes the need for greater awareness of the immediate and long-term cardiovascular implications of viral infection and the significant gaps in knowledge that future research will need to address…